Commonly applied Chemo Therapy for instance also harms healthy tissues.
Modern therapies strive to target tumors directly, minimizing harm to healthy tissues. However, identifying targets that are unique to cancer cells and not found in healthy cells is a major challenge.
Recent research reveals that tumors harbor their own unique communities of microbes – a distinct microbiome. Especially Fusobacterium nucleatum provides a specific target for our precision therapy.
We've engineered a powerful weapon that consists of two key parts. First, an affinity protein acts like a homing device, specifically binding to Fusobacterium nucleatum within the tumor. Second, a linked enzyme converts a harmless prodrug into a toxic compound only at the tumor site, destroying cancer cells while minimizing side effects.
